Evidence Aid & CEBM Partnership Launch
Thursday 27th October
Rewley House, 1 Wellington Square, Oxford
Evidence Aid, an international charity based in Oxford, and the Centre for Evidence-Based Medicine are officially launching their partnership on Thursday 27th October 2016.
The event will address the key issue of the need for humanitarian interventions to be as evidence-based as possible to be as effective as possible. The panel will be chaired by Evidence Aid Trustee Lady Deborah Dixon and features:
- Dr Kamal R. Mahtani, Deputy Director of CEBM – The partnership and its importance to the humanitarian sector.
- Professor Michael Clarke, Queen’s University Belfast and a Founder of Evidence Aid – The importance of robust synthesised evidence.
- Jeroen Jansen, Director of Evidence Aid – The hurdles towards a more evidence based approach.
- Keynote speaker Mukesh Kapila CBE, Professor of Global Health and Humanitarian Affairs at the University of Manchester and Special Adviser to the World Humanitarian summit, who declared that “effectiveness is a moral issue and a duty” at the World Humanitarian Summit in Istanbul this summer. He will be addressing the moral dimension to evidence-based humanitarianism.
There will be a Q&A session afterwards.
Light refreshments will be served from 5.00pm with official proceedings 5.30-6.30pm, drinks/canapés thereafter, concluding approximately 7.15pm.
All are welcome but places are limited. Students with an interest in humanitarian aid or disaster relief are invited. Tickets for admission will be required.
For further information about the event, please contact Jane Higgins.
Oxford Alumni Weekend
Saturday 17 September
St Luke’s Chapel, Radcliffe Observatory Quarter, Woodstock Road
The Centre for Evidence-Based Medicine, in collaboration with the Nuffield Department for Primary Care Health Sciences and Kellogg College, are pleased to announce two open events during Alumni Weekend.
Delivering Evidence-Based Medicine to Schools – Chaired by Dr Kamal R. Mahtani (Deputy Director, CEBM)
There are a substantial number of healthcare claims made every day, many through mainstream media. These can have distinct effects on individuals, their families and the wider society. Given the vast number of claims that are generated, it is important that healthcare professionals are proficient in “critical appraisal”, which allows a skilled judgement to be made as to whether these claims are useful or relevant to patients.
But why should these skills be limited to just healthcare professionals? A number of organisations provide support and resources that allow members of the general public to gain sufficient skills to be able to challenge health care claims. For example, NHS Choices provides a guide on how to read health news, highlighting the reasons why it is important not to “automatically believe the headline”. Similarly, Sense about Science have developed the askforevidence.org campaign to help members of the public identify what is, and what is not, reliable evidence upon which to make healthcare claims.
The Centre for Evidence Based Medicine is a not-for-profit organisation dedicated to the practice, teaching and dissemination of high quality evidence-based medicine to improve healthcare in everyday clinical practice. One of the current ongoing projects is to foster critical thinking about healthcare claims in school children. The EvIdeNce into Schools and TEachINg (EinSTein) project involves a number of partners who share that agenda including TestingTreatments, the Education Endowment Foundation, James Lind Initiative and Informed Healthcare Choices Group.
In this session we will provide some background information to the work being done with school children, as well as hear from members of the Education Endowment Foundation and Ask for Evidence campaign.
Pete Henderson, Education Endowment Fund
Sarah Pannell, Lingfield School & Centre for Evidence-Based Medicine
Hamish Chalmers, Doctoral Researcher & Ask For Evidence Ambassador
REGISTRATION OPEN – please book to avoid disappointment. The event is open to all, including members of the public.
Harms and Healthcare – Chaired by Dr Annette Plüddemann (Director MSc in EBHC)
Here we will present a series of talks by Henry Drysdale, Dr Marcy McCall MacBain and Professor Carl Heneghan on whether medicine is broken, whether device regulation is creating seriously harmful devices and whether our personal choices are damaging our health.
Henry Drysdale is a graduate entry medical student at Oxford and a member of the COMPare team led by Dr Ben Goldacre.
COMPare monitors “outcome switching”: when trialists report different outcomes from those they originally registered, and don’t explain the changes. This can decrease the quality of the evidence on which clinical decisions are made. In 6 weeks of monitoring, COMPare found 87% of reports contained undeclared discrepancies between prespecified and reported outcomes. Through correction letters and correspondence on every misreported trial, the COMPare team found widespread misunderstanding at the heart of the issue.
Visit the COMPare website for more details about their team, methods, results and blog.
Dr Marcy McCall MacBain has an active interest in women’s health and will question the dramatic increase in all types of cosmetic procedures. What happens when they go wrong? What are the adverse effects? Why is there a lack of evidence and outcome metrics? And are we (as healthcare professionals and young women) allocating healthcare spending to the appropriate age-related issues?
Professor Carl Heneghan – All Meshed Up: How regulation of medical devices is harming patients:
Working with Dutch undercover investigation journalists, Professor Heneghan exposed how the regulation of medical devices is lacking. Professor Heneghan has extensive expertise in device regulation and will highlight how dangerous and defective devices can easily make it on to the market with little or no evidence, and how they cause serious harm.
REGISTRATION OPEN – please book to avoid disappointment. The event is open to all, including members of the public.
Kellogg College Gaudy Dinner
18:45 Drinks reception; 19:15 Formal dinner
Members of Kellogg College and friends are invited to join us as we celebrate the annual Alumni Weekend in Oxford with this special dinner.
Dress code: Black Tie (with gowns for Fellows of Kellogg College)
The cost of this dinner is £43.00.
BOOKING ESSENTIAL. Please note: The Gaudy Dinner is NOT covered by student dinner allowances.
Harms in Healthcare 2015
2:30pm September 19th 2015, at Oxford Museum of Natural History
The Centre for Evidence Based Medicine at the Nuffield Department of Primary Care Health Sciences will present a unique insight on the individual and institutional self-interests in research, combined with increased global competition that are currently leading to substantial harms in healthcare. In addition, a growing body of research on adverse drug reactions has uncovered that there is considerable room for improvement in the public understanding of this little known area. We will question whether medicine is broken – do patients and the public ever fully understand what doctors, academics and regulators have been permitted to do to them and what would their reaction be? How the media contribute to harms and the growing problem of overdiagnosis, creating patients from a healthy population. We’ll also discuss the impact of a £500 million deficit in the public purse from stockpiling the controversial flu drug Tamiflu.
This event is part of the University of Oxford’s alumni weekend. The event is open to all, including members of the public.
Talks from Dr Jeffrey Aronson, Prof Carl Heneghan , Dr Ben Goldacre , Bethany Shinkins, Tim Muntinga and Dr Kamal Mahtani
The Widespread Dangers of Bad Medicine – Guy Collender reports from the Harms in Healthcare event, part of Oxford University’s Alumni Weekend on Saturday 19 September 2015.
Deadly Devices and Dangerous Drugs 2014
Improving the evidence that underpins devices and drugs used for routine clinical care.
On Saturday 20th September 2014, Deadly Devices and Dangerous Drugs was presented to a full lecture theatre at Oxford Museum of Natural History by Carl Heneghan, Jeff Aronson, Deb Cohen, Ben Goldacre, chaired by Sharon Mickan.
Is it surprising that individual and institutional self-interests in research, combined with increased global competition, undermine scientific integrity?
Regulatory systems that aim to underpin health research are under considerable strain. Keeping track of, and explaining why research goes wrong, is an important priority for delivery of sustained health outcomes, and support of the conduct of high quality research.
Deb Cohen’s investigative work has highlighted that revision rates for hip joints are at least double that of other materials. Despite earlier reports from Australia that the implant was causing problems, the metal on metal hip continued to be widely used.
Ben Goldacre believes medicine is broken. “And genuinely believes that if patients and the public ever fully understand what has been done to them – what doctors, academics and regulators have permitted – they will be angry.”
Jeff Aronson has spent a lifetime researching adverse drug reactions, and perceives there is considerable room for improvement in our understanding
Whilst, Carl Heneghan has shown that the regulatory framework for drugs is so lax, it is not surprizing that devices over time have proven to be deadly.
Jeff Aronson is Reader in Clinical Pharmacology at the University of Oxford, Honorary Consultant Physician to the Oxford University Hospitals NHS Trust, and a Fellow of Green-Templeton College, Oxford. His research interests include all aspects of clinical pharmacology, especially adverse drug reactions and interactions and monitoring therapeutic interventions. He is President Emeritus of the British Pharmacological Society and a past Editor-in-Chief of the British Journal of Clinical Pharmacology. He is the editor and author of many books, including “The Oxford Handbook of Practical Drug Therapy” and “Meyler’s Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions”.
Deborah Cohen is investigations editor of the BMJ, which she joined after studying medicine at both Manchester University and Universite de Rennes. Whilst at university she intercalated in medical journalism, edited her university publication and worked on a newspaper in Ghana covering health and human rights. Deborah has reported from a variety of places including the West Bank, Kenya and Ethiopia. As investigations editor of the BMJ, much of her work has focused on drug and medical device regulation, access to clinical data and conflicts of interest. She has collaborated on documentaries with the BBC, Channel 4 News and Dispatches, and Al-Jazeera, as well has having working jointly with the Bureau of Investigative Journalism.
Ben Goldacre is a best-selling author, broadcaster, campaigner, medical doctor and academic who specialises in unpicking the misuse of science and statistics by journalists, politicians, quacks, drug companies, and more. His recent book , Bad Pharma, is on bad behaviour in the pharmaceutical industry and medicine more broadly: it is now a top ten UK best seller. He is the co-founder of the AllTrials campaign – now supported by over 50,000 individuals, 120 patient groups, GSK, and all major academic and medical bodies in the UK – working towards a concrete fix for the ongoing problem of clinical trial results being withheld. He has toured theatres and rock venues and given over 300 talks in the past 5 years.
Carl Heneghan is professor in Evidence-Based Medicine, Director of the Centre of Evidence-Based Medicine and a General Practitioner. He has had an association with the Centre for Evidence-Based Medicine since 1995 and is a fellow of Kellogg College. His Research projects involve determining the evidence base using unpublished data for infection treatments and investigating the evidence base for publication bias and drug and device regulation.