Roche funded IPD meta-analysis (Dobson et al) published in Lancet – covering editorial refers to as “independent”.

Roche funded IPD meta-analysis (Dobson et al) published in Lancet – covering editorial refers to as “independent”. Announcement Date: January 1, 2015

“The re-analysis was funded by an unrestricted grant from Roche but was done by an independent research group, thus seeking to overcome the suggested bias associated with industry-funded studies” Kelly et al editorial.

Dobson et al. Acknowledgments

This study was funded by the Multiparty Group for Advice on Science (MUGAS) Foundation through an unrestricted grant from Roche Pharmaceuticals. Neither party had a role in analysis, interpretation, reporting or the decision to submit for publication. We thank Roche for providing the data and answering data specific queries.


Dobson J, Whitley RJ, Pocock S, Monto AS. Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet 2015; 385: 1729–37.

Interpretation

Our findings show that oseltamivir in adults with influenza accelerates time to clinical symptom alleviation, reduces risk of lower respiratory tract complications, and admittance to hospital, but increases the occurrence of nausea and vomiting.


Linked editorial:

Heath Kelly, Benjamin J Cowling Influenza: the rational use of oseltamivir The Lancet, Volume 385, Issue 9979, 2–8 May 2015, Pages 1700-1702 PDF (177 K)

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