CEBM Publications on PuBMed in 2015

  1. The efficacy of supplementation with the novel medical food, Souvenaid, in patients with Alzheimer’s disease: A systematic review and meta-analysis of randomized clinical trials. Onakpoya IJ, Heneghan CJ. Nutr Neurosci. 2015 Dec 7. [Epub ahead of print]
  1. Missed opportunities for diagnosis: lessons learned from diagnostic errors in primary care. Goyder CR, Jones CH, Heneghan CJ, Thompson MJ. Br J Gen Pract. 2015 Dec;65(641):e838-44. doi: 10.3399/bjgp15X687889.
  1. Oxfordshire Women and Their Children’s Health (OxWATCH): protocol for a prospective cohort feasibility study. Harrison S, Petrovic G, Chevassut A, Brook L, Higgins N, Kenworthy Y, Selwood M, Snelgar T, Arnold L, Boardman H, Heneghan C, Leeson P, Redman C, Granne I. BMJ Open. 2015 Nov 9;5(11):e009282. doi: 10.1136/bmjopen-2015-009282.
  1. Creatinine point-of-care testing for detection and monitoring of chronic kidney disease: primary care diagnostic technology update. Gbinigie O, Price CP, Heneghan C, Van den Bruel A, Plüddemann A. Br J Gen Pract. 2015 Nov;65(640):608. doi: 10.3399/bjgp15X687613. No abstract available.
  1. Antivirals, pandemic planning, and failure to heed calls for trial data. Heneghan C, Goldacre B. BMJ. 2015 Oct 22;351:h5635. doi: 10.1136/bmj.h5635. No abstract available.
  1. Accuracy of methods for detecting an irregular pulse and suspected atrial fibrillation: A systematic review and meta-analysis. Taggar JS, Coleman T, Lewis S, Heneghan C, Jones M. Eur J Prev Cardiol. 2015 Oct 13. pii: 2047487315611347. [Epub ahead of print] Review.
  1. Oseltamivir for influenza. Doshi P, Heneghan C, Jefferson T. Lancet. 2015 Sep 19;386(9999):1134-5. doi: 10.1016/S0140-6736(15)00202-0. No abstract available.
  1. Rethinking the appraisal and approval of drugs for type 2 diabetes. Naci H, Lehman R, Wouters OJ, Goldacre B, Yudkin JS. BMJ. 2015 Oct 9;351:h5260. doi: 10.1136/bmj.h5260. No abstract available.
  1. Fixing flaws in science must be professionalized. Goldacre B, Brown T. J Clin Epidemiol. 2015 Jul 3. pii: S0895-4356(15)00331-5. doi: 10.1016/j.jclinepi.2015.06.018. [Epub
  1. Corticosteroids for the common cold. Hayward G, Thompson MJ, Perera R, Del Mar CB, Glasziou PP, Heneghan CJ. Cochrane Database Syst Rev. 2015 Oct 13;10:CD008116. doi: 10.1002/14651858.CD008116.pub3. Review.
  1. Antibiotics for preventing lower respiratory tract infections in high-risk children aged 12 years and under. Onakpoya IJ, Hayward G, Heneghan CJ. Cochrane Database Syst Rev. 2015 Sep 26;9:CD011530. doi: 10.1002/14651858.CD011530.pub2. Review.
  1. The Diagnostic Value of Capillary Refill Time for Detecting Serious Illness in Children: A Systematic Review and Meta-Analysis. Fleming S, Gill P, Jones C, Taylor JA, Van den Bruel A, Heneghan C, Roberts N, Thompson M. PLoS One. 2015 Sep 16;10(9):e0138155. doi: 10.1371/journal.pone.0138155. eCollection 2015.
  1. Protocol for an overview of systematic reviews of interventions to reduce unscheduled hospital admissions among adults. Bobrovitz N, Onakpoya I, Roberts N, Heneghan C, Mahtani KR. BMJ Open. 2015 Aug 21;5(8):e008269. doi: 10.1136/bmjopen-2015-008269.
  1. Medication errors detected in non-traditional databases: types of errors in methotrexate dosing as listed in four different Danish registers. Perregaard H, Aronson JK, Dalhoff K, Hellebek A. Eur J Clin Pharmacol. 2015 Nov;71(11):1375-9. doi: 10.1007/s00228-015-1910-3. Epub 2015 Aug 11.
  1. Cato Guldberg and Peter Waage, the history of the Law of Mass Action, and its relevance to clinical pharmacology. Ferner RE, Aronson JK. Br J Clin Pharmacol. 2015 Jul 14. doi: 10.1111/bcp.12721. [Epub ahead of print] Review.
  1. The law of mass action and the pharmacological concentration-effect curve: resolving the paradox of apparently non-dose-related adverse drug reactions. Aronson JK, Ferner RE. Br J Clin Pharmacol. 2015 Jun 28. doi: 10.1111/bcp.12706. [Epub ahead of print] Review.
  1. Toward standardized reporting of drug interactions: the READI checklist for anecdotal reports. Aronson JK. Expert Rev Clin Pharmacol. 2015;8(4):399-409. doi: 10.1586/17512433.2015.1049598. Epub 2015 May 27.
  1. A licence to cure. Aronson JK, Ferner RE. BMJ. 2015 Apr 1;350:h1723. doi: 10.1136/bmj.h1723. No abstract available.
  1. Moving Focus from Weight to Health. What Are the Components Used in Interventions to Improve Cardiovascular Health in Children? Friedemann Smith C, Heneghan C, Ward A. PLoS One. 2015 Aug 11;10(8):e0135115. doi: 10.1371/journal.pone.0135115. eCollection 2015.
  1. Yoga in adult cancer: an exploratory, qualitative analysis of the patient experience. McCall M, Thorne S, Ward A, Heneghan C. BMC Complement Altern Med. 2015 Jul 22;15:245. doi: 10.1186/s12906-015-0738-9.
  1. Yoga for Health-Related Quality of Life in Adult Cancer: A Randomized Controlled Feasibility Study. McCall M, McDonald M, Thorne S, Ward A, Heneghan C. Evid Based Complement Alternat Med. 2015;2015:816820. doi: 10.1155/2015/816820. Epub 2015 Jun 11.
  1. Cochrane corner: vitamin K for improved anticoagulation control in patients receiving warfarin. Mahtani KR, Nunan D, Heneghan C. Heart. 2015 Nov 1;101(21):1689-90. doi: 10.1136/heartjnl-2014-307133. Epub 2015 Jul 1. No abstract available.
  1. Effectiveness, safety and costs of orphan drugs: an evidence-based review. Onakpoya IJ, Spencer EA, Thompson MJ, Heneghan CJ. BMJ Open. 2015 Jun 24;5(6):e007199. doi: 10.1136/bmjopen-2014-007199. Erratum in: BMJ Open. 2015;5(10):e007199corr1.
  1. How medicine is broken, and how we can fix it. Goldacre B, Heneghan C. BMJ. 2015 Jun 23;350:h3397. doi: 10.1136/bmj.h3397. No abstract available.
  1. Cohort study of Anticoagulation Self-Monitoring (CASM): a prospective study of its effectiveness in the community. Ward A, Tompson A, Fitzmaurice D, Sutton S, Perera R, Heneghan C. Br J Gen Pract. 2015 Jul;65(636):e428-37. doi: 10.3399/bjgp15X685633. Epub 2015 Jun 15.
  1. The Efficacy of Mindfulness-Based Interventions in Primary Care: A Meta-Analytic Review. Demarzo MM, Montero-Marin J, Cuijpers P, Zabaleta-Del-Olmo E, Mahtani KR, Vellinga A, Vicens C, López-Del-Hoyo Y, García-Campayo J. Ann Fam Med. 2015 Nov;13(6):573-82. doi: 10.1370/afm.1863. Review.
  1. Indications for Use of Damage Control Surgery in Civilian Trauma Patients: A Content Analysis and Expert Appropriateness Rating Study.Roberts DJ, Bobrovitz N, Zygun DA, Ball CG, Kirkpatrick AW, Faris PD, Brohi K, D’Amours S, Fabian TC, Inaba K, Leppäniemi AK, Moore EE, Navsaria PH, Nicol AJ, Parry N, Stelfox HT.Ann Surg. 2015 Oct 1.
  1. The use of cognitive interviews to revise the Quality of Trauma Care Patient-Reported Experience Measure (QTAC-PREM)Bobrovitz N, Santana MJ, Kline T, Kortbeek J, Stelfox HT. Qual Life Res. 2015 Aug;24(8):1911-9. doi: 10.1007/s11136-015-0919-5. Epub 2015 Jan 15.
  1. Indications for use of damage control surgery and damage control interventions in civilian trauma patients: A scoping review.Roberts DJ, Bobrovitz N, Zygun DA, Ball CG, Kirkpatrick AW, Faris PD, Stelfox HT. J Trauma Acute Care Surg. 2015 Jun;78(6):1187-96. doi: 10.1097/TA.0000000000000647. Review.
  1. Implementation of an Advanced Nursing Directive for Children With Right Lower Quadrant Pain: Identifying Those Requiring Further Investigation and Improving Flow Metrics. Thompson GC, Kwong S, Bobrovitz N, Yang S, Pols EK, Stang AS, Eccles RC, Kazoleas V. Pediatr Emerg Care. 2015 Jul 28. [Epub ahead of print]
  1. Self-monitoring blood pressure in hypertension, patient and provider perspectives: A systematic review and thematic synthesis. Fletcher BR, Hinton L, Hartmann-Boyce J, Roberts NW, Bobrovitz N, McManus RJ. Patient Educ Couns. 2015 Aug 28. pii: S0738-3991(15)30063-X. doi: 10.1016/j.pec.2015.08.026.
  1. Indications for use of thoracic, abdominal, pelvic, and vascular damage control interventions in trauma patients: A content analysis and expert appropriateness rating study. Roberts DJ, Bobrovitz N, Zygun DA, Ball CG, Kirkpatrick AW, Faris PD, Parry N, Nicol AJ, Navsaria PH, Moore EE, Leppäniemi AK, Inaba K, Fabian TC, D’Amours S, Brohi K, Stelfox HT.J Trauma Acute Care Surg. 2015 Oct;79(4):568-79. doi: 10.1097/TA.0000000000000821.
  1. Protocol for an overview of systematic reviews of interventions to reduce unscheduled hospital admissions among adults. Bobrovitz N, Onakpoya I, Roberts N, Heneghan C, Mahtani KR. BMJ Open. 2015 Aug 21;5(8):e008269. doi: 10.1136/bmjopen-2015-008269.
  1. Marjolin’s ulcer. Choa R, Rayatt S, Mahtani K. BMJ. 2015 Aug 19;351:h3997. doi: 10.1136/bmj.h3997. No abstract available.
  1. Physical activity and obesity editorial: is exercise pointless or was it a pointless exercise? Mahtani KR, McManus J, Nunan D. Br J Sports Med. 2015 Aug;49(15):969-70. doi: 10.1136/bjsports-2015-095005. Epub 2015 Jun 18. No abstract available.
  2. Estimating the diagnostic accuracy of rheumatoid factor in UK primary care: a study using the Clinical Practice Research Datalink. Miller A, Nightingale AL, Sammon CJ, Mahtani KR, Holt TA, McHugh NJ, Luqmani RA. Rheumatology (Oxford). 2015 Oct;54(10):1882-9. doi: 10.1093/rheumatology/kev131. Epub 2015 Jun 8.
  3. The first center for evidence-based medicine in Lithuania: an opportunity to change culture and improve clinical practice. Beinortas T, Bauza K, Howick J, Nunan D, Mahtani KR. J Evid Based Med. 2015 May;8(2):108-10. doi: 10.1111/jebm.12156.
  4. Missing laboratory test data in electronic general practice records: analysis of rheumatoid factor recording in the clinical practice research datalink. Sammon CJ, Miller A, Mahtani KR, Holt TA, McHugh NJ, Luqmani RA, Nightingale AL. Pharmacoepidemiol Drug Saf. 2015 May;24(5):504-9. doi: 10.1002/pds.3750. Epub 2015 Mar 10.
  5. Supporting patients to self-monitor their oral anticoagulation therapy: recommendations based on a qualitative study of patients’ experiences. Tompson A, Heneghan C, Fitzmaurice D, Sutton S, Harrison S, Ward A. Br J Gen Pract. 2015 Jul;65(636):e438-46. doi: 10.3399/bjgp15X685645. Epub 2015 Jun 15.
  6. Heterogeneity of prognostic studies of 24-hour blood pressure variability: systematic review and meta-analysis. Taylor KS, Heneghan CJ, Stevens RJ, Adams EC, Nunan D, Ward A. PLoS One. 2015 May 18;10(5):e0126375. doi: 10.1371/journal.pone.0126375. eCollection 2015.
  7. The effect of wind turbine noise on sleep and quality of life: A systematic review and meta-analysis of observational studies. Onakpoya IJ, O’Sullivan J, Thompson MJ, Heneghan CJ. Environ Int. 2015 Sep;82:1-9. doi: 10.1016/j.envint.2015.04.014. Epub 2015 May 16.
  8. Relationship between altitude and the prevalence of hypertension in Tibet: a systematic review. Mingji C, Onakpoya IJ, Perera R, Ward AM, Heneghan CJ. Heart. 2015 Jul;101(13):1054-60. doi: 10.1136/heartjnl-2014-307158. Epub 2015 May 7. Review.
  9. Funding source and primary outcome changes in clinical trials registered on ClinicalTrials.gov are associated with the reporting of a statistically significant primary outcome: a cross-sectional study. Ramagopalan SV, Skingsley AP, Handunnetthi L, Magnus D, Klingel M, Pakpoor J, Goldacre B. Version 2. F1000Res. 2015 Mar 26 [revised 2015 Apr 24];4:80. doi: 10.12688/f1000research.6312.2.
  10. Insertion torque recordings for the diagnosis of contact between orthodontic mini-implants and dental roots: protocol for a systematic review. Meursinge Reynders R, Ladu L, Ronchi L, Di Girolamo N, de Lange J, Roberts N, Plüddemann A. Syst Rev. 2015 Apr 2;4:39. doi: 10.1186/s13643-015-0014-6.
  11. Blood CEA levels for detecting recurrent colorectal cancer. Nicholson BD, Shinkins B, Pathiraja I, Roberts NW, James TJ, Mallett S, Perera R, Primrose JN, Mant D. Cochrane Database Syst Rev. 2015 Dec 10;12:CD011134. [Epub ahead of print] Review.
  12. Monitoring ocular hypertension, how much and how often? A cost-effectiveness perspective. Hernández R, Burr JM, Vale L, Azuara-Blanco A, Cook JA, Banister K, Tuulonen A, Ryan M; Surveillance of Ocular Hypertension Study group. Br J Ophthalmol. 2015 Dec 11. pii: bjophthalmol-2015-306757. doi: 10.1136/bjophthalmol-2015-306757. [Epub ahead of print]
  13. An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care. Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Breen M, Bradley B, Kelly S, Yao G, Raftery J, Mant D, Little P. Health Technol Assess. 2015 Sep;19(72):1-150. doi: 10.3310/hta19720.
  14. Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial. Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Kelly S, Yao G, Raftery J, Mant D, Little P. CMAJ. 2015 Sep 22;187(13):961-9. doi: 10.1503/cmaj.141608. Epub 2015 Jul 27.
  15. Incentives for smoking cessation.Cahill K, Hartmann-Boyce J, Perera R. Cochrane Database Syst Rev. 2015 May 18;5:CD004307. doi: 10.1002/14651858.CD004307.pub5.
  16. Symptoms, unmet needs, psychological well-being and health status in survivors of prostate cancer: implications for redesigning follow-up. Watson E, Shinkins B, Frith E, Neal D, Hamdy F, Walter F, Weller D, Wilkinson C, Faithfull S, Wolstenholme J, Sooriakumaran P, Kastner C, Campbell C, Neal R, Butcher H, Matthews M, Perera R, Rose P. BJU Int. 2015 Mar 27. doi: 10.1111/bju.13122. [Epub ahead of print]
  17. Effectiveness of school-based smoking prevention curricula: systematic review and meta-analysis. Thomas RE, McLellan J, Perera R. BMJ Open. 2015 Mar 10;5(3):e006976. doi: 10.1136/bmjopen-2014-006976. Review.Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study. Vale CL, Rydzewska LH, Rovers MM, Emberson JR, Gueyffier F, Stewart LA; Cochrane IPD Meta-analysis Methods Group. BMJ. 2015 Mar 6;350:h1088. doi: 10.1136/bmj.h1088.
  18. Personalised care planning for adults with chronic or long-term health conditions. Coulter A, Entwistle VA, Eccles A, Ryan S, Shepperd S, Perera R. Cochrane Database Syst Rev. 2015 Mar 3;3:CD010523. doi: 10.1002/14651858.CD010523.pub2. Review.
  19. Personalising results from large trials. Perera R, Stevens RJ. BMJ. 2015 Feb 20;350:h553. doi: 10.1136/bmj.h553. No abstract available.
  20. Ueno method substaging pT1 colorectal adenocarcinoma by depth and width measurement: an inter-observer study. Wang LM, Guy R, Fryer E, Kartsonaki C, Gill P, Hughes C, Szuts A, Perera R, Chetty R, Mortensen N. Colorectal Dis. 2015 Jan 24. doi: 10.1111/codi.12910.
  21. Implications of lower risk thresholds for statin treatment in primary prevention: analysis of CPRD and simulation modelling of annual cholesterol monitoring. McFadden E, Stevens R, Glasziou P, Perera R. Prev Med. 2015 Jan;70:14-6. doi: 10.1016/j.ypmed.2014.11.004. Epub 2014 Nov 18.
  22. Testing treatments interactive (TTi): helping to equip the public to promote better research for better health care. Chen Y, Chalmers I; TTi Editorial Alliance. J Evid Based Med. 2015 May;8(2):98-102. doi: 10.1111/jebm.12155.
  23. How to get all trials reported: audit, better data, and individual accountability. Goldacre B. PLoS Med. 2015 Apr 14;12(4):e1001821. doi: 10.1371/journal.pmed.1001821. eCollection 2015 Apr. No abstract available.
  24. A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32. Park S, Khan NF, Hampshire M, Knox R, Malpass A, Thomas J, Anagnostelis B, Newman M, Bower P, Rosenthal J, Murray E, Iliffe S, Heneghan C, Band A, Georgieva Z. Med Teach. 2015 May 6:1-20. [Epub ahead of print]
  25. Accuracy of self-monitored blood pressure for diagnosing hypertension in primary care. Nunan D, Thompson M, Heneghan CJ, Perera R, McManus RJ, Ward A. J Hypertens. 2015 Apr;33(4):755-62; discussion 762. doi: 10.1097/HJH.0000000000000489.
  26. GP training in out-of-hours care: implications for the future workforce. Hayward G, Drinkwater J, El-Gohary M, Burgess H, Heneghan C. Educ Prim Care. 2015 Mar;26(2):95-101.
  27. Patient self-management in primary care patients with mild COPD – protocol of a randomised controlled trial of telephone health coaching. Sidhu MS, Daley A, Jordan R, Coventry PA, Heneghan C, Jowett S, Singh S, Marsh J, Adab P, Varghese J, Nunan D, Blakemore A, Stevens J, Dowson L, Fitzmaurice D, Jolly K. BMC Pulm Med. 2015 Feb 22;15:16. doi: 10.1186/s12890-015-0011-5.
  28. The Effect of Grapefruits (Citrus paradisi) on Body Weight and Cardiovascular Risk Factors: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Onakpoya I, O’Sullivan J, Heneghan C, Thompson M.Crit Rev Food Sci Nutr. 2015 Apr 16:0. [Epub ahead of print]
  29. The effect of cactus pear (Opuntia ficus-indica) on body weight and cardiovascular risk factors: a systematic review and meta-analysis of randomized clinical trials. Onakpoya IJ, O’Sullivan J, Heneghan CJ. Nutrition. 2015 May;31(5):640-6. doi: 10.1016/j.nut.2014.11.015. Epub 2014 Dec 19.
  30. Self-Screening and Non-Physician Screening for Hypertension in Communities: A Systematic Review. Fleming S, Atherton H, McCartney D, Hodgkinson J, Greenfield S, Hobbs FD, Mant J, McManus RJ, Thompson M, Ward A, Heneghan C. Am J Hypertens. 2015 Nov;28(11):1316-24. doi: 10.1093/ajh/hpv029. Epub 2015 Mar 23.
  31. Home-use faecal immunochemical testing: primary care diagnostic technology update. Nicholson BD, Thompson M, Price CP, Heneghan C, Plüddemann A. Br J Gen Pract. 2015 Mar;65(632):156-8. doi: 10.3399/bjgp15X684229. No abstract available.
  32. Accuracy of methods for diagnosing atrial fibrillation using 12-lead ECG: A systematic review and meta-analysis. Taggar JS, Coleman T, Lewis S, Heneghan C, Jones M. Int J Cardiol. 2015 Apr 1;184:175-83. doi: 10.1016/j.ijcard.2015.02.014. Epub 2015 Feb 10.
  33. Email for clinical communication between healthcare professionals. Goyder C, Atherton H, Car M, Heneghan CJ, Car J. Cochrane Database Syst Rev. 2015 Feb 20;2:CD007979. doi: 10.1002/14651858.CD007979.pub3. Review.
  34. Yoga in adult cancer: a pilot survey of attitudes and beliefs among oncologists. McCall MC, Ward A, Heneghan C. Curr Oncol. 2015 Feb;22(1):13-9. doi: 10.3747/co.22.2129.
  35. Commentary on Cochrane review of neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Jones M, Jefferson T, Doshi P, Del Mar C, Heneghan C, Onakpoya I. Clin Microbiol Infect. 2015 Mar;21(3):217-21. doi: 10.1016/j.cmi.2014.10.011. Epub 2014 Oct 29.
  36. Delays in the post-marketing withdrawal of drugs to which deaths have been attributed: a systematic investigation and analysis. Onakpoya IJ, Heneghan CJ, Aronson JK. BMC Med. 2015 Feb 5;13:26. doi: 10.1186/s12916-014-0262-7
  37. Effect of the novel functional fibre, polyglycoplex (PGX), on body weight and metabolic parameters: A systematic review of randomized clinical trials. Onakpoya IJ, Heneghan CJ. Clin Nutr. 2015 Dec;34(6):1109-14. doi: 10.1016/j.clnu.2015.01.004. Epub 2015 Jan 13.
  38. Identification of children at risk of influenza-related complications in primary and ambulatory care: a systematic review and meta-analysis. Gill PJ, Ashdown HF, Wang K, Heneghan C, Roberts NW, Harnden A, Mallett S. Lancet Respir Med. 2015 Feb;3(2):139-49. doi: 10.1016/S2213-2600(14)70252-8. Epub 2014 Dec 4. Erratum in: Lancet Respir Med. 2015 Feb;3(2):e3.
Carl Heneghan

About Carl Heneghan

Carl is Professor of EBM & Director of CEBM at the University of Oxford. He is also a GP and tweets @carlheneghan. He has an active interest in discovering the truth behind health research findings and also blogs on Trust The Evidence at www.carlheneghan.com

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