The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare.
Evidence-based thinking and why it matters
Views expressed may represent the views of the author and not necessarily those of CEBM as a group
How studying the history and philosophy of EBM helps
There were about 20,000 POWs in the camp, of whom a quarter were British. The diet was about 600 calories a day and we all had diarrhoea. In addition we had severe epidemics of typhoid, diphtheria, infections, jaundice, and sand-fly fever…
Doctor Igho Onakpoya and Professor Carl Heneghan attended the World Health Organization in Geneva, on the 5th of November 2013.
A common mantra in statistics is that ‘association is not causation’. However, in reality it is causation that we are really interested in when researching a phenomenon in Medicine.
Does A cause B? If I take X will I prevent Y?
These apparently innocuous questions have profound philosophical implications.
My favourite EBP course of the year (every year!) For me, as a tutor, it is probably one of my favourite teaching roles throughout the academic year. The course began with an introduction from the CEBM director Professor Carl Heneghan. Carl reminded us, amongst many other things, of the simple steps in EBP: Ask, Acquire, Appraise, Apply, Assess.
In the EUROPA trial 12,218 patients were randomized to receive perindopril or placebo. 9.9% of the participants in the ‘placebo’ group died or had a heart attack, whereas only 8% in the experimental group died or had a heart attack: roughly a 2% absolute effect size. You would have to treat 50 patients with the drug to get one with a positive outcome.
“A man begins cutting his teeth the first time he bites off more than he can chew” Herb Caen
This was very much my experience when teaching about ’Study Designs’ on day one of the Practice of Evidence Based Health Care. Active, enthusiastic and engaged audiences, in my opinion, always make for a better teaching (and hopefully learning) experience.
This is a significant document which highlights the importance of clinical trials for the health of a nation, but also for the overall economy. There has been a substantial drop in the number of trials being undertaken in the UK; yet, when you ask the population if they want to participate in a trial: 72% say they do.
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Everywhere we look, there seem to be problems in synthesising and organising knowledge for use. We know that the latest research evidence is not routinely implemented and that at times, we don’t change practice to prevent harm.
It’s been another big year for the MSc in EBHC. There has been a change of leadership but the momentum of great education continues. At the beginning of the 2012-2013 academic year we had 61 continuing MSc students. We also had 37 students enrolled onto the Postgraduate Diploma in Health Research.
Evidence-Based Health Care MSc Graduate Ahmed Elkhadem publishes.
Carl Heneghan and John Balla discuss papers on Diagnostic reasoning.
New from the admissions team and CEBM team