Transmission dynamics of children with COVID-19 in China
COVID-19: Transmission dynamics of children with COVID-19 in China. Spencer EA, Heneghan C.
Published on June 27, 2020
Transmission Dynamics of COVID-19
||Zhen-Dong Y, Gao-Jun Z, Run-Ming J, et al. Clinical and transmission dynamics characteristics of 406 children with coronavirus disease 2019 in China: A review [published online ahead of print, 2020 Apr 28]. J Infect. 2020;S0163-4453(20)30241-3. doi:10.1016/j.jinf.2020.04.030
||Person to person
Children were more likely to have asymptomatic infections, milder conditions, faster recovery, and better prognosis than adults
Out of 406 confirmed paediatric cases, 77 (19%) were asymptomatic. Familial cluster transmission accounted for 359 cases (88%); non-familial contact transmission was found in 17 cases (4.2%); 30 cases had an unknown history (7.4%).
Among the 406 cases, 55 were tested for anal swab virus nucleic acid, and 45 (82%) cases were positive. A 10-year-old boy with no symptoms and negative nucleic acid samples from the respiratory had positive stool samples were positive for nucleic acids after 17 days
There were no major abnormalities in laboratory tests, and lymphocytes were not reduced as in adults.
What did they do?
This was a review of the literature on the clinical and transmission dynamics characteristics relating to paediatric cases of COVID-19 in China. 37 publications were included describing features of 406 cases. Descriptive statistics were used to summarize COVID-19 demographics, propagation dynamics, and clinical data. Categorical variables were expressed in numbers and proportions.
The authors note that this may not be a comprehensive summary of all data on paediatric cases.
|Clearly defined setting
||Demographic characteristics described
||Follow-up length was sufficient
||Transmission outcomes assessed
||Main biases are taken into consideration
What else should I consider?
This review did not show characteristics of the included studies nor evaluate their quality and is as such of limited value.
About the authors