This theme aims to:

– Improve the evidence base that informs how we routinely diagnose, overdiagnosis and screen conditions in clinical care

– Identify and assessing new diagnostic technologies

– Prevent the harms of too much medicine

Examples of our research in this area are shown below

Diagnostic for antimicrobial resistance

Tackling antimicrobial resistance is an important global public health challenge.  The World Health Organisation has highlighted that antimicrobial resistance is

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Anti-Microbial Resistance Diagnostics Paper

There is no doubt that tackling antibiotic resistance is of major public health importance to global health systems. This report highlights the considerable number of new diagnostic technologies in development to underpin the rational prescribing of antibiotics.

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Clinical Prediction Rules in Practice

Background One way of implementing Evidence-Based Medicine for diagnosis and prognosis in clinical practice is to use appropriately validated and

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Self-monitoring of oral anticoagulation

Cochrane Library Podcast Carl Heneghan, University of Oxford Centre for Evidence-Based Medicine, discusses a new Cochrane review of self monitoring

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WHO guidelines on Cardiovascular risk

The WHO Global NCD Action Plan 2013-2020 provides a road map to attain nine voluntary global targets, including that of

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Oxfordshire Women & Children’s Health

Little is known about the impact of pre-pregnancy factors and pregnancy itself on women’s long-term health and wellbeing. Some specific

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Paeds emergency admissions

Researchers: Gill PJ, Goldacre MJ, Mant D, Heneghan C, Thomson A, Seagroatt V, Harnden A

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Rheumatoid Factor in RA

Researchers: Mahtani KR, Miller A, Rivero-Arias O, Heneghan C, Price CP, Thompson M, Plüddemann A, Luqmani R.

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Packaging to improve adherence

Researchers: Mahtani KR, Heneghan CJ, Glasziou PP, Perera R.

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Optimal loading dose of warfarin

Warfarin is commonly prescribed to prevent blot clots in patients with medical conditions such as atrial fibrillation, heart valve replacement

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Assessing Diagnostic Technologies

The Diagnostic Horizon Scan Programme is part of the National Institute for Health Research Diagnostic Evidence Cooperative Oxford (NIHR DEC

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