COVID-19: Transmission within a family cluster by presymptomatic carriers in China
COVID-19: Transmission within a family cluster by presymptomatic carriers in China. Spencer EA, Heneghan C.
Published on July 23, 2020
Transmission Dynamics of COVID-19
||Guoqing Qian, Naibin Yang, Ada Hoi Yan Ma, Liping Wang, Guoxiang Li, Xueqin Chen, Xiaomin Chen. COVID-19 Transmission Within a Family Cluster by Presymptomatic Carriers in China Clinical Infectious Diseases. ciaa316 2020
||Supported by the Natural Science Foundation of Zhejiang Province
Within a family cluster of eight cases among nine family members, clinical manifestations varied from asymptomatic to severe pneumonia, and timing of symptom onset varied.
Among nine family members, eight were laboratory-confirmed with COVID-19, and a 6-year-old child had no evidence of infection.
Among the eight cases, one adult and a 13-month-old infant were asymptomatic; one adult was diagnosed as having severe pneumonia.
What did they do?
A family cluster of coronavirus disease 2019 (COVID-19) caused by a presymptomatic case. 9 family members lived in three households, in Zhejiang province, outside Wuhan.
This is a report of a small cluster of cases within one family.
|Clearly defined setting
||Demographic characteristics described
||Follow-up length was sufficient
||Transmission outcomes assessed
||Main biases are taken into consideration
What else should I consider?
About the authors
Carl is Professor of EBM & Director of CEBM at the University of Oxford. He is also a GP and tweets @carlheneghan. He has an active interest in discovering the truth behind health research findings
Dr Elizabeth Spencer; MMedSci, PhD. Epidemiologist, Nuffield Department for Primary Care Health Sciences, University of Oxford.